Formulation: A solution in water
Formal Name: 2,3-dihydro-2-oxo-adenosine 5′-(tetrahydrogen triphosphate), tetrasodium salt
Purity: ≥95%
Formula Markup: C10H12N5O14P3 • 4Na
Formula Weight: 611,1
Shelf life (days): 730
Notes: Isoguanosine-5'-O-triphosphate is an isomer of guanosine 5'-triphosphate (GTP; Item No. 16060) and a phosphorylated form of crotonoside (Item No. 28219). Unlike GTP, isoguanosine-5'-O-triphosphate does not stimulate microtubule assembly.{68439} Isoguanosine-5'-O-triphosphate (2 mM) inhibits transcription and induces T to C mutations in a reverse transcriptase assay.{66441} It has been used to determine the substrate specificity of phosphofructokinase and mutT homolog 1 (MTH1).{66442,66443}