Kumatakenin, CAS 3301-49-3

Formulation: A solid

Formal Name: 5-hydroxy-2-(4-hydroxyphenyl)-3,7-dimethoxy-4H-1-benzopyran-4-one

Purity: ≥98%

Formula Markup: C17H14O6

Formula Weight: 314,3

Shelf life (days): 1460

CAS Number: 3301-49-3

Notes: Kumatakenin is a flavonoid that has been found in S. aromaticum and has diverse biological activities.{64525,64526,64527} It inhibits the growth of SKOV3 and A2780 ovarian cancer cells in a concentration-dependent manner.{64525} It induces apoptosis and decreases the protein levels of the tumor-associated macrophage (TAM) recruitment factors MCP-1 and RANTES in SKOV3 cells when used at a concentration of 30 µM. Kumatakenin (10 µM) inhibits neutrophil elastase activity and inhibits antigen-induced RBL-2H3 mast cell degranulation (IC50 = 80.4 µM).{64526} It is active against S. aureus, E. coli, P. aeruginosa, and L. monocytogenes (MICs = 64, 128, 128, and 512 µg/ml, respectively) and acts synergistically with ampicillin (Item No. 14417), gentamicin, or erythromycin (Item No. 16486) to reduce L. monocytogenes biofilm formation.{64527}

• Artikelnummer: CAY35514-10
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 35514-10
• Green Labware: Nein
• Verpackungseinheit: 10 mg
• Mengeneinheit: STK
• Methode: Reinstoffe