LATS-IN-1, CAS 1424635-83-5

Formulation: A solid

Formal Name: N-[3-(phenylmethyl)-2(3H)-thiazolylidene]-1H-pyrrolo[2,3-b]pyridine-3-carboxamide

Purity: ≥98%

Formula Markup: C18H14N4OS

Formula Weight: 334,4

Shelf life (days): 1460

CAS Number: 1424635-83-5

Notes: LATS-IN-1 is an inhibitor of large tumor suppressor kinase 1 (LATS1) and LATS2 (IC50 = 2 nM for both), key regulators of Hippo regenerative signaling.{64599} It inhibits phosphorylation of YES1-associated transcriptional regulator (YAP1) in serum-starved HEK293A cells (EC50 = 510 nM). LATS-IN-1 (10 µM) increases the proliferation of Müller glial cells and isolated mouse cardiomyocytes.

• Artikelnummer: CAY36623-1
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 36623-1
• Green Labware: Nein
• Verpackungseinheit: 1 mg
• Mengeneinheit: STK
• Methode: Reinstoffe