LEI-110, CAS 2313525-90-3

Formulation: A solid

Formal Name: α-oxo-N-[2-[4-[[5-(trifluoromethyl)-2-pyridinyl]oxy]phenyl]ethyl]-benzenepentanamide

Purity: ≥98%

Formula Markup: C25H23F3N2O3

Formula Weight: 456,5

Shelf life (days): 1460

CAS Number: 2313525-90-3

Notes: LEI-110 is an inhibitor of adipose phospholipase A2 (AdPLA2; IC50 = 100 nM).{68085} It also inhibits HRas-like suppressor 2 (HRASL2), retinoid acid receptor responder protein 3 (RARRES3), and calcium-independent N-acyltransferase (iNAT; IC50s = 158, 158, and 25 nM, respectively). LEI-110 (10 µM) decreases arachidonic acid (Item Nos. 90010 / 90010.1 / 10006607) levels in U2OS cells expressing human AdPLA2 and prevents oleic acid-induced increases in lipid droplet formation in HepG2 cells.

• Artikelnummer: CAY36789-10
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 36789-10
• Green Labware: Nein
• Verpackungseinheit: 10 mg
• Mengeneinheit: STK
• Methode: Reinstoffe