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Biological Activity: ME0328 is a potent and selective PARP3 inhibitor with IC50 of 0.89 µM for PARP3, vs. 6.3 µM for PARP1.
CAS Number: 1445251-22-8
Description: ME0328 is a potent and selective PARP inhibitor with about 7-fold selectivity over PARP3 over PARP1.
Purity: ≥98% by HPLC
Solubility: Soluble in DMSO
Storage Stability: Store at or below -20°C. Solid form is stable at least 12 months from date of receipt, when stored as directed. Do not store aqueous solutions for more than one day.
Target: PARP3
Biosafety Level: Not applicable (BSL-1)
References: Lindgren, A.E., et al. ACS Chem Biol. 2013 Aug 16;8(8):1698-703.