Methazolamide, CAS 554-57-4

Formulation: A crystalline solid

Formal Name: N-[5-(aminosulfonyl)-3-methyl-1,3,4-thiadiazol-2(3H)-ylidene]-acetamide

Purity: ≥98%

Formula Markup: C5H8N4O3S2

Formula Weight: 236,3

Shelf life (days): 1460

CAS Number: 554-57-4

Notes: Methazolamide is a carbonic anhydrase inhibitor (IC50 = 130 nM).{36164} It reduces intraocular pressure and cerebrospinal fluid flow in a rat model of glaucoma. Methazolamide reduces electroshock-induced seizures in rats with an ED50 value of 19.2 mg/kg.{36165} It also inhibits production of reactive oxygen species (ROS) in a primary cortical neuron (PCN) cellular model of subarachnoid hemorrhage (SAH) and reduces cerebral edema in a mouse model of SAH.{36166} Formulations containing methazolamide have been used for the treatment of glaucoma.

• Artikelnummer: CAY23413-10
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 23413-10
• Green Labware: Nein
• Verpackungseinheit: 10 g
• Mengeneinheit: STK