Methidathion, CAS 950-37-8

Formulation: A solid

Formal Name: S-[(5-methoxy-2-oxo-1,3,4-thiadiazol-3(2H)-yl)methyl]phosphorodithioic acid, O,O-dimethyl ester

Purity: ≥98%

Formula Markup: C6H11N2O4PS3

Formula Weight: 302,3

Shelf life (days): 1460

CAS Number: 950-37-8

Notes: Methidathion is an organophosphate insecticide that inhibits insect cholinesterase.{42230} It reduces cattle lice (L. vituli, D. bovis, and H. eurysternus) infestation by 99.1% when administered topically at a dose of 3.5 mg/kg.{42226} Methidathion is selectively toxic to lice over cattle, only inhibiting cattle plasma acetylcholinesterase activity by 20% with no effect on survival when administered topically at a dose of 24 mg/kg. It increases sister chromatid exchange (SCE) in a concentration-dependent manner and induces cell cycle arrest at the M1 phase in V79 cells when used at a concentration of 40 μg/ml.{42227} Dietary administration of methidathion (1.4-4.7 mg/kg) increases alanine aminotransferase, aspartate aminotransferase, sorbitol dehydrogenase, and alkaline phosphatase activity, inhibits cholinesterase, and induces chronic liver inflammation in male beagle dogs.{42228} It also induces loss of striation and myocytolysis of cardiomyocytes and reduces serum cholinesterase activity in rats when administered orally at a dose of 5 mg/kg.{42229}

• Artikelnummer: CAY24144-250
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 24144-250
• Green Labware: Nein
• Verpackungseinheit: 250 mg
• Mengeneinheit: STK