MKT-077, CAS 147366-41-4

Formulation: A crystalline solid

Formal Name: 1-ethyl-2-[[3-ethyl-5-(3-methyl-2(3H)-benzothiazolylidene)-4-oxo-2-thiazolidinylidene]methyl]-pyridinium, monochloride

Purity: ≥95%

Formula Markup: C21H22N3OS2 • Cl

Formula Weight: 432

Shelf life (days): 1460

CAS Number: 147366-41-4

Notes: MKT-077 is a cationic rhodacyanine dye that demonstrates antiproliferative activity against cancer cell lines (EC50s = 1.4-2.2 µM in vitro) through its ability to inhibit members of the heat shock protein 70 (Hsp70) family of molecular chaperones.{30109} It has been shown to bind to an allosteric site conserved in Hsp70 family members, interfering with ATP hydrolysis and abrogating the interaction of the chaperone with the tumor suppressor p53.{30110,30111}

• Artikelnummer: CAY14395-25
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 14395-25
• Green Labware: Nein
• Verpackungseinheit: 25 mg
• Mengeneinheit: STK