Moexiprilat, CAS 103775-14-0

Formulation: A solid

Formal Name: (3S)-2-[(2S)-2-[[(1S)-1-carboxy-3-phenylpropyl]amino]-1-oxopropyl]-1,2,3,4-tetrahydro-6,7-dimethoxy-3-isoquinolinecarboxylic acid

Purity: ≥95%

Formula Markup: C25H30N2O7

Formula Weight: 470,5

Shelf life (days): 1460

CAS Number: 103775-14-0

Notes: Moexiprilat is an inhibitor of angiotensin-converting enzyme (ACE; IC50 = 2.1 nM) and an active metabolite of the prodrug moexipril (Item No. 21255).{33383} It is formed from moexipril in vivo by side chain ester hydrolysis.{33382} Moexiprilat (10 nM) prevents the estrone- or angiotensin II-stimulated proliferation of primary neonatal rat cardiac fibroblasts.{68435} It reduces mean arterial blood pressure and increases the levels of atrial natriuretic peptide, a marker of hypertension, in ovariectomized mice when administered at a dose of 50 mg/kg per day.{68436}

• Artikelnummer: CAY38047-5
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 38047-5
• Green Labware: Nein
• Verpackungseinheit: 5 mg
• Mengeneinheit: STK