Nanaomycin A, CAS 52934-83-5

Formulation: A solid

Formal Name: (1S,3R)-3,4,5,10-tetrahydro-9-hydroxy-1-methyl-5,10-dioxo-1H-naphtho[2,3-c]pyran-3-acetic acid

Purity: ≥80%

Formula Markup: C16H14O6

Formula Weight: 302,3

Shelf life (days): 1460

CAS Number: 52934-83-5

Notes: Nanaomycin A is a quinone bacterial metabolite originally isolated from Streptomyces that has antimicrobial activity.{45188} It inhibits the growth of a variety of bacteria (MICs = P. falciparum (IC80 = 0.033 µM).{45188,57310} Nanaomycin A is a selective DNA methyltransferase 3B (DNMT3B) inhibitor that inhibits proliferation of HCT116, A549, and HL-60 cancer cells (IC50s = 0.4, 4.1, and 0.8 µM, respectively).{57311} Nanaomycin A promotes the differentiation of human induced pluripotent stem (iPS) cells into hepatoblasts at the definitive endoderm cell-to-hepatoblast stage, but not the iPS cell-to-definitive endoderm cell stage, when used at a concentration of 1 µM.{57312}

• Artikelnummer: CAY9001479-10
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 9001479-10
• Green Labware: Nein
• Verpackungseinheit: 10 mg
• Mengeneinheit: STK