Pep2-8, CAS 1541011-97-5

Formulation: A solid

Formal Name: (3S,6S,9S,12S,15S)-15-((2S,5S,8S,11S,14S,17S)-2-((1H-indol-3-yl)methyl)-11-benzyl-8,17-bis((R)-1-hydroxyethyl)-5-(hydroxymethyl)-14-isopropyl-4,7,10,13,16,19-hexaoxo-3,6,9,12,15,18-hexaazaicosanamido)-3-(((S)-1-(((S)-1-amino-3-methyl-1-oxobutan-2-yl)amino)-3-(1H-indol-3-yl)-1-oxopropan-2-yl)carbamoyl)-12-(2-carboxyethyl)-9-(4-hydroxybenzyl)-6-isobutyl-5,8,11,14-tetraoxo-4,7,10,13-tetraazaoctadecanedioic acid

Purity: ≥95%

Formula Markup: C83H110N16O24

Formula Weight: 1715,9

Shelf life (days): 1460

CAS Number: 1541011-97-5

Notes: Pep2-8 is a peptide inhibitor of proprotein convertase subtilisin kexin type 9 (PCSK9; IC50 = 1.4 µM).{62852} It reverses PCSK9-induced decreases in surface LDL receptor levels and restores uptake of LDL in HepG2 cells in a concentration-dependent manner.

• Artikelnummer: CAY36923-1
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 36923-1
• Green Labware: Nein
• Verpackungseinheit: 1 mg
• Mengeneinheit: STK
• Methode: Reinstoffe