Quinaprilat, CAS 82768-85-2

Formulation: A solid

Formal Name: (3S)-2-[(2S)-2-[[(1S)-1-carboxy-3-phenylpropyl]amino]-1-oxopropyl]-1,2,3,4-tetrahydro-3-isoquinolinecarboxylic acid

Purity: ≥90%

Formula Markup: C23H26N2O5

Formula Weight: 410,5

Shelf life (days): 1460

CAS Number: 82768-85-2

Notes: Quinaprilat is an inhibitor of angiotensin-converting enzyme (ACE; IC50 = 0.06 nM) and an active metabolite of the ACE inhibitor prodrug quinapril (Item No. 21439).{65330,65331} It inhibits calcium overload and rod to round cell shape change induced by lysophosphatidylcholine (LPC) in isolated rat cardiomyocytes when used at concentrations of 20 and 50 µM.{65331} Quinaprilat (3 µg/kg) reduces the frequency of ventricular fibrillation in a dog model of myocardial ischemia and reperfusion injury.{65332} It also reduces blood pressure and proteinuria in rat models of uranyl nitrate- or 5/6 nephrectomy-induced chronic renal failure when administered at a dose of 0.1 mg/kg.{65333}

• Artikelnummer: CAY36007-25
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 36007-25
• Green Labware: Nein
• Verpackungseinheit: 25 mg
• Mengeneinheit: STK
• Methode: Reinstoffe