Formulation: A solution in ethanol
Formal Name: N-[(2R)-2-(dimethylamino)-2-phenylethyl]-3,5-difluoro-benzamide
Purity: ≥98%
Formula Markup: C17H18F2N2O
Formula Weight: 304,3
Shelf life (days): 365
CAS Number: 2771208-83-2
Notes: (R)-HTS-3 is an inhibitor of lysophosphatidylcholine acyltransferase 3 (LPCAT3; IC50 = 0.09 µM), an enzyme involved in the synthesis of C20:4-containing phospholipids.{65488} It reduces the incorporation of arachidonic acid-d8 (Item No. 390010) into phospholipids when used at concentrations of 1, 3, and 10 µM. (R)-HTS-3 (10 µM) reduces RSL3-induced ferroptosis in HT-1080 and 786-O cancer cells.