Resveratrol, CAS 501-36-0

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Background: Resveratrol (also known as SRT-501) is a phytoalexin derived from grapes and other food products with antioxidant and potential chemopreventive activities. Resveratrol induces phase II drug-metabolizing enzymes (anti-initiation activity); mediates anti-inflammatory effects and inhibits cyclooxygenase and hydroperoxidase functions (anti-promotion activity); and induces promyelocytic leukemia cell differentiation (anti-progression activity), thereby exhibiting activities in three major steps of carcinogenesis. This agent may inhibit TNF-induced activation of NF-κB; in a dose- and time-dependent manner.

CAS Number: 501-36-0

Description: Resveratrol is a phytoalexin produced naturally by several plants with anti-cancer, anti-inflammatory, blood-sugar-lowering and other beneficial cardiovascular effects. Resveratrol activates sirtuin subtype 1 (SIRT-1). SIRT1 activation has been reported to inhibit tumorigenesis and tumor cell proliferation.

Purity: ≥98% by HPLC

Solubility: Soluble in DMSO

Storage Stability: Store at or below -20°C. Solid form is stable at least 12 months from date of receipt, when stored as directed. Do not store aqueous solutions for more than one day.

Target: SIRT1

Biosafety Level: Not applicable (BSL-1)

References: 1. Svajger U, et al. Int Rev Immunol. 2012 Jun;31(3):202-22.
2. Whitlock NC, et al. Nutr Cancer. 2012;64(4):493-502.
3. Juan ME, et al. Pharmacol Res. 2012 Jun;65(6):584-91.
4. Turan B, et al. J Bioenerg Biomembr. 2012 Apr;44(2):281-96.

• Artikelnummer: BPS27642-3
• Hersteller: BPS Bioscience
• Hersteller Artikelnummer: 27642-3
• Green Labware: Nein
• Verpackungseinheit: 500 mg
• Mengeneinheit: STK