Ro 0335, CAS 867365-76-2

Formulation: A solid

Formal Name: N-[4-(aminosulfonyl)-2-chlorophenyl]-4-bromo-3-(3-chloro-5-cyanophenoxy)-2-fluoro-benzeneacetamide

Purity: ≥98%

Formula Markup: C21H13BrCl2FN3O4S

Formula Weight: 573,2

Shelf life (days): 1460

CAS Number: 867365-76-2

Notes: Ro 0335 is a non-nucleoside reverse transcriptase inhibitor (NNRTI) and an active metabolite of the antiviral prodrug elsulfavirine.{69064} It inhibits HIV-1 reverse transcriptase in a cell-free assay and the replication of HIV-1 in MT-4 cells (IC50s = 8.1 and 1.1 nM, respectively). Ro 0335 also selectively inhibits human carbonic anhydrase VII (CAVII; Ki = 9.7 nM) over human CAI and CAIII-VI (Kis = >125 nM for all) but also inhibits human CAII, CAIX, CAXII, CAXIII, and CAXIV (Kis = 35.5, 72.1, 62.3, 52.2, and 15.4 nM, respectively).{69065}

• Artikelnummer: CAY36124-100
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 36124-100
• Green Labware: Nein
• Verpackungseinheit: 100 mg
• Mengeneinheit: STK
• Methode: Reinstoffe