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Rolipram , CAS 61413-54-5
Rolipram , CAS 61413-54-5
Artikelnummer
BPS27005
Verpackungseinheit
10 mg
Hersteller
BPS Bioscience
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Biological Activity: Rolipram inhibited PDE4 with IC50=1µM using the BPS Bioscience PDE4A Assay Kit (Cat. # 60340).
CAS Number: 61413-54-5
Description: Rolipram is a selective, cell permeable inhibitor of cAMP-specific phosphodiesterase 4 (PDE4). PDE4 enzymes inactivate cyclic AMP (cAMP) via hydrolysis to 5'-AMP. Rolipram has two enantiomeric forms, R(-) and S(+). This product is the racemic mixture of the two enantiomers.
Format: White solid.
Purity: ≥95% by HPLC.
Solubility: Soluble in DMSO (25 mg/ml warm) and Ethanol (25 mg/ml warm).
Storage Stability: Store at or below -20°C. Solid form is stable at least 12 months from date of receipt, when stored as directed. Do not store aqueous solutions for more than one day.
Biosafety Level: Not applicable (BSL-1)
References: 1. Parker, C.A., et al., Synapse 55: 270 -279 (2005)
2. Barnard, J.W., et al., J. Appl. Physiol. 77: 774 - 781 (1994)
3. DeMarch, Z., et al., Neurobiol. Dis. 30: 375 - 387 (2008)
Biological Activity: Rolipram inhibited PDE4 with IC50=1µM using the BPS Bioscience PDE4A Assay Kit (Cat. # 60340).
CAS Number: 61413-54-5
Description: Rolipram is a selective, cell permeable inhibitor of cAMP-specific phosphodiesterase 4 (PDE4). PDE4 enzymes inactivate cyclic AMP (cAMP) via hydrolysis to 5'-AMP. Rolipram has two enantiomeric forms, R(-) and S(+). This product is the racemic mixture of the two enantiomers.
Format: White solid.
Purity: ≥95% by HPLC.
Solubility: Soluble in DMSO (25 mg/ml warm) and Ethanol (25 mg/ml warm).
Storage Stability: Store at or below -20°C. Solid form is stable at least 12 months from date of receipt, when stored as directed. Do not store aqueous solutions for more than one day.
Biosafety Level: Not applicable (BSL-1)
References: 1. Parker, C.A., et al., Synapse 55: 270 -279 (2005)
2. Barnard, J.W., et al., J. Appl. Physiol. 77: 774 - 781 (1994)
3. DeMarch, Z., et al., Neurobiol. Dis. 30: 375 - 387 (2008)
| Artikelnummer | BPS27005 |
|---|---|
| Hersteller | BPS Bioscience |
| Hersteller Artikelnummer | 27005 |
| Green Labware | Nein |
| Verpackungseinheit | 10 mg |
| Mengeneinheit | STK |
| Produktinformation (PDF) | Download |
| MSDS (PDF) |
|
Immer für Sie da
Gernot Ensinger, M.Sc.
Laurent Haze
