Ruxolitinib, Phosphate, CAS 1092939-17-7

Products from BPS Bioscience require a minimum order value above 400€

CAS Number: 1092939-17-7

Description: Ruxolitinib, also known as INCB18424, is a potent and selective Janus kinase JAK1 and JAK2 inhibitor, with IC50s of 5.9 nM and 5.7 nM, respectively. It inhibited IL-6 and IL-23 effects at concentrations less than 50 nM. Ruxolitinib was effective in the rat adjuvant arthritis model and multiple murine models of arthritis.

Format: white powder.

Purity: ≥99%

Solubility: Soluble in DMSO at 200 mg/ml; very poorly soluble in ethanol; soluble in water at 8 mg/ml

Storage Stability: Store at or below -20°C. Solid form is stable at least 12 months from date of receipt, when stored as directed. Do not store aqueous solutions for more than one day.

Warnings: Avoid freeze/thaw cycles.

Biosafety Level: Not applicable (BSL-1)

References: Fridman, J.S., et al. J. Immunol. 184: 5298-5307 (2010).

• Artikelnummer: BPS27059-1
• Hersteller: BPS Bioscience
• Hersteller Artikelnummer: 27059-1
• Green Labware: Nein
• Verpackungseinheit: 25 mg
• Mengeneinheit: STK