T-1095, CAS 209746-59-8

T-1095, CAS 209746-59-8
Artikelnummer
CAY37284-5
Verpackungseinheit
5 mg
Hersteller
Cayman Chemical

Verfügbarkeit: wird geladen...
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Formulation: A crystalline solid

Formal Name: 3-(5-benzofuranyl)-1-[2-hydroxy-6-[[6-O-(methoxycarbonyl)-β-D-glucopyranosyl]oxy]-4-methylphenyl]-1-propanone

Purity: ≥98%

Formula Markup: C26H28O11

Formula Weight: 516,5

Shelf life (days): 1460

CAS Number: 209746-59-8

Notes: T-1095 is an inhibitor of sodium-glucose cotransporter 1 (SGLT1) and SGLT2 (IC50s = 22.8 and 2.3 µM, respectively).{68183} Dietary administration of T-1095 (0.01% w/w) reduces blood glucose and HbA1c levels in a rat model of diabetes induced by streptozotocin (Item No. 13104). It suppresses the development of hyperglycemia and hypertriglyceridemia and reduces HbA1c levels in the KKAγ mouse model of type 2 diabetes. T-1095 exacerbates post-infarction cardiac dysfunction in a rat model of left anterior descending coronary artery ligation-induced myocardial infarction.{68154}
Mehr Informationen
Artikelnummer CAY37284-5
Hersteller Cayman Chemical
Hersteller Artikelnummer 37284-5
Green Labware Nein
Verpackungseinheit 5 mg
Mengeneinheit STK
Methode Reinstoffe
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