Valtrate, CAS 18296-44-1

Formulation: A solution in chloroform

Formal Name: butanoic acid, 3-methyl-1′-[(1S,2′R,6S,7aS)-4-[(acetyloxy)methyl]-6,7a-dihydrospiro[cyclopenta[c]pyran-7(1H),2′-oxirane]-1,6-diyl]ester

Purity: ≥98%

Formula Markup: C22H30O8

Formula Weight: 422,5

Shelf life (days): 365

CAS Number: 18296-44-1

Notes: Valtrate is a valepotriate that has been found in Valeriana and has diverse biological activities.{31362,61169,66037} It inhibits nuclear export of influenza virus ribonucleoprotein complex (vRNP) in HeLa cells when used at a concentration of 3.6 µM and inhibits influenza virus infection in MDCK cells (IC50 = 0.19 µM).{31362} Valtrate is cytotoxic to GLC-4 lung and COLO 320 colorectal cancer cells (IC50s = 1.4 and 3 µM, respectively).{61169} It increases the number of entries into, and percentage of time spent in, the open arms of the elevated plus maze, indicating anxiolytic-like activity, and decreases serum corticosterone levels in rats when administered at a dose of 10 mg/kg.{66037}

• Artikelnummer: CAY36522-10
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 36522-10
• Green Labware: Nein
• Verpackungseinheit: 10 mg
• Mengeneinheit: STK
• Methode: LC-MS