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Vinpocetine , CAS 42971-09-5
Vinpocetine , CAS 42971-09-5
Artikelnummer
BPS27778-1
Verpackungseinheit
100 mg
Hersteller
BPS Bioscience
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Biological Activity: Vinpocetine is selective for PDE1: IC50 = 21 µM, vs. PDE3: IC50 = 300 µM (bovine heart). Vinpocetine inhibits differently the various subtypes of PDE1 (IC50 from 8 to 50 µm). It is also reported to inhibit PDE7B with an IC50 of 60 µM, and it can have effects on Heat Shock Factor 1 (EC5050 = 195 µM) and ADH-induced lipid peroxidation ( IC50 = 137 µM in rat brain microsome).
CAS Number: 42971-09-5
Description: Vinpocetine, also known as Cavinton or ethyl apovincaminate, is a specific inhibitor of basal and calmodulin-activated PDE1. Also blocks voltage-gated Na+ channels.
Format: white solid
Solubility: Soluble in ethanol up to 50 mM or DMSO at 5 mg/ml
Storage Stability: Store at or below -20°C. Solid form is stable at least 12 months from date of receipt, when stored as directed. Do not store aqueous solutions for more than one day.
Target: PDE1
Warnings: Photosensitive; protect from light.
Biosafety Level: Not applicable (BSL-1)
Biological Activity: Vinpocetine is selective for PDE1: IC50 = 21 µM, vs. PDE3: IC50 = 300 µM (bovine heart). Vinpocetine inhibits differently the various subtypes of PDE1 (IC50 from 8 to 50 µm). It is also reported to inhibit PDE7B with an IC50 of 60 µM, and it can have effects on Heat Shock Factor 1 (EC5050 = 195 µM) and ADH-induced lipid peroxidation ( IC50 = 137 µM in rat brain microsome).
CAS Number: 42971-09-5
Description: Vinpocetine, also known as Cavinton or ethyl apovincaminate, is a specific inhibitor of basal and calmodulin-activated PDE1. Also blocks voltage-gated Na+ channels.
Format: white solid
Solubility: Soluble in ethanol up to 50 mM or DMSO at 5 mg/ml
Storage Stability: Store at or below -20°C. Solid form is stable at least 12 months from date of receipt, when stored as directed. Do not store aqueous solutions for more than one day.
Target: PDE1
Warnings: Photosensitive; protect from light.
Biosafety Level: Not applicable (BSL-1)
| Artikelnummer | BPS27778-1 |
|---|---|
| Hersteller | BPS Bioscience |
| Hersteller Artikelnummer | 27778-1 |
| Green Labware | Nein |
| Verpackungseinheit | 100 mg |
| Mengeneinheit | STK |
| Produktinformation (PDF) |
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| MSDS (PDF) |
|
Immer für Sie da
Gernot Ensinger, M.Sc.
Laurent Haze
