Strophanthidin, CAS 66-28-4

Formulation: A solid

Formal Name: 3β,5β,14-trihydroxy-19-oxo-card-20(22)-enolide

Purity: ≥90%

Formula Markup: C23H32O6

Formula Weight: 404,5

Shelf life (days): 1460

CAS Number: 66-28-4

Notes: Strophanthidin is a cardenolide that has been found in A. schimperi and has diverse biological activities.{41362,42765,25457,65940} It is an inhibitor of N-acetyltransferase (IC50 = ~1.2 µM).{41362} Strophanthidin (1 µM) reduces maximal Na+/K+-ATPase pump activity and cell attachment and increases cell death in MDCK-C7 cells.{42765} It decreases the levels of steroid receptor coactivator 3 (SRC-3) in MCF-7 breast cancer cells when used at a concentration of 500 nM.{25457} Strophanthidin (50 µM) increases calcium efflux and sarcoplasmic reticulum calcium levels in a voltage-clamp assay using isolated and perfused guinea pig hearts.{65940}

• Artikelnummer: CAY39244-250
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 39244-250
• Verpackungseinheit: 250 mg
• Mengeneinheit: STK