Tat-QFNP12 (trifluoroacetate salt)

Formulation: A solid

Formal Name: L-tyrosylglycyl-L-arginyl-L-lysyl-L-lysyl-L-arginyl-L-arginyl-L-glutaminyl-L-arginyl-L-arginyl-L-arginyl-L-valyl-L-lysyl-L-lysyl-L-glutamyl-L-alanyl-L-glutamyl-L-leucyl-L-aspartyl-L-lysyl-L-tyrosyl-L-leucyl-L-glutamic acid, trifluoroacetate salt

Purity: ≥90%

Formula Markup: C130H225N47O35 • XCF3COOH

Formula Weight: 3006,5

Shelf life (days): 1460

Notes: Tat-QFNP12 is a peptide containing a transcriptional transactivator (Tat) transmembrane domain and an inhibitor of the protein-protein interaction between N-Myc downstream regulated gene 2 (NDRG2) and the protein phosphatase Mg2+/Mn2+ dependent 1A (PPM1A).{69428} It decreases the loss of blood-brain barrier endothelial tight junctions induced by increased levels of matrix metalloproteinase-9 (MMP-9), reduces cerebral edema, as well as increases spontaneous activity and symmetry of limb movement, in an endovascular puncture-induced mouse model of subarachnoid hemorrhage when administered at a dose of 20 mg/kg.

• Artikelnummer: CAY38845-25
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 38845-25
• Green Labware: Nein
• Verpackungseinheit: 25 mg
• Mengeneinheit: STK