Formulation: A solution in water
Formal Name: 5-[[hydroxy[[hydroxy(phosphonooxy)phosphinyl]oxy]phosphinyl]amino]-1-naphthalenesulfonic acid, P′′→5′-ester with uridine, trisodium salt
Purity: ≥95%
Formula Markup: C19H19N3O17P3S • 3Na
Formula Weight: 755,3
Shelf life (days): 730
Notes: Uridine-5'-O-triphosphoro-γ-1-(5-sulfonic acid)naphthylamidate (UTP-γ-AmNS) is a fluorescent derivative of the nucleotide and dual purinergic P2Y2 and P2Y4 receptor agonist UTP (Item No. 9003530).{69412} It has been used in high-throughput screening (HTS) assays for inhibitors of bacterial RNA polymerase activity. Upon incorporation of UMP in RNA, γ-AmNS-PPi is released, which has an emission at 465 nm upon excitation at 360 nm and a higher fluorescence intensity than UTP-γ-AmNS.