Product Description: (1R,3S)-RSL3 is the less active (1R,3S)-enantiomer of RSL3 ((1S,3R)-RSL3). (1R,3S)-RSL3 and RSL3 induce cell death in HT22 wild-type cells with EC50 values of 5.2 µM and 0.004 µM, rspectively[1].
Applications: Cancer-programmed cell death
Formula: C23H21ClN2O5
References: [1]Shin D, et al. Nrf2 inhibition reverses resistance to GPX4 inhibitor-induced ferroptosis in head and neck cancer. Free Radic Biol Med. 2018 Dec;129:454-462.
CAS Number: 1219810-13-5
Molecular Weight: 440.88
Research Area: Cancer
Solubility: 10 mM in DMSO
Target: Others