3-(4-Hydroxy-1-oxoisoindolin-2-yl)piperidine-2,6-dione, CAS 1061604-41-8

Product Description: Lenalidomide-4-OH is the Lenalidomide-based cereblon (CRBN) ligand used in the recruitment of CRBN protein. Lenalidomide-4-OH can be connected to the ligand for protein by a linker to form PROTAC.

Applications: Cancer-programmed cell death

Formula: C13H12N2O4

References: [1]Scheepstra M, et al. Bivalent Ligands for Protein Degradation in Drug Discovery. Comput Struct Biotechnol J. 2019;17:160-176. Published 2019 Jan 25./[2]Nalawansha DA, et al. PROTACs: An Emerging Therapeutic Modality in Precision Medicine. Cell Chem Biol. 2020;27(8):998-985.

CAS Number: 1061604-41-8

Molecular Weight: 260.25

Compound Purity: 98.57

Research Area: Cancer

Solubility: DMSO : 50 mg/mL (ultrasonic)

Target: Ligands for E3 Ligase

• Artikelnummer: MEXHY-W076696-1G
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-W076696-1G
• Green Labware: Nein
• Verpackungseinheit: 1 g
• Mengeneinheit: STK