3-Fluoro-evodiamine glucose

Product Description: 3-Fluoro-evodiamine glucose (Compound 8) is an evodiamine-glucose conjugate. 3-Fluoro-evodiamine glucose activates the expression of glucose transporter 1 (GLUT1), and inhibits topoisomerase I/II. 3-Fluoro-evodiamine glucose induces apoptosis and arrests the cell cycle at G2/M phase. 3-Fluoro-evodiamine glucose exhibits antitumor efficacy in vivo and in vitro, without significant toxicity[1].

Applications: Cancer-programmed cell death

Formula: C25H26FN3O7

References: [1]Wu Z, et al., Design of Evodiamine-Glucose Conjugates with Improved In Vivo Antitumor Activity. J Med Chem. 2024 May 9;67(9):7373-7384.

Molecular Weight: 499.49

Research Area: Cancer

Solubility: 10 mM in DMSO

Target: Apoptosis;GLUT;Topoisomerase

• Artikelnummer: MEXHY-161501-0
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-161501-0
• Green Labware: Nein
• Verpackungseinheit: Get quote
• Mengeneinheit: STK