4-oxo-2-Nonenal, CAS 103560-62-9

Description: 4-hydroxy Nonenal is a lipid peroxidation product derived from oxidized ω-6 polyunsaturated fatty acids such as arachidonic acid and linoleic acid. [1] [2] It exhibits various biological activities such as cytotoxicity, growth inhibiting activity, genotoxicity, and chemotactic activity and has been widely used as a marker of lipid peroxidation.[1][2][3] 4-oxo-2-Nonenal is a more recently identified product of lipid peroxidation.[4][5][6] It actively modifies histidine and lysine residues on proteins and causes protein cross-linking. [7][8] 4-oxo-2-Nonenal also modifies 2’-deoxyguanosine, further implicating lipid peroxidation in mutagenesis and carcinogenesis.[4]

CAS Number: 103560-62-9

Formula: C9H14O2

Molecular Weight: 154,209

References: Pryor, W.A., and Porter, N.A. Suggested mechanisms for the production of 4-hydroxy-2-nonenal from the autoxidation of polyunsaturated fatty acids. Free Radical Biology & Medicine 8, 541-543 (1990).

• Artikelnummer: TGMT35646-1mg
• Hersteller: TargetMol Chemicals
• Hersteller Artikelnummer: T35646-1mg
• Green Labware: Nein
• Verpackungseinheit: 1 mg
• Mengeneinheit: STK