Product Description: α-Amylase/α-Glucosidase-IN-12 (compound 10k) is a dual inhibitor targeting α-glucosidase and α-amylase with IC50 of 34.52 nM and 24.62 nM, respectively. α-Amylase/α-Glucosidase-IN-12 is an inhibitor designed based on triazolo[4,3-b][1,2,4]triazine and has the potential to be used in diabetes research.[11][1].
Formula: C19H13F3N6OS
References: [1]Seyfi S, et al. Synthesis, biological activities, and molecular docking studies of triazolo[4,3-b]triazine derivatives as a novel class of α-glucosidase and α-amylase inhibitors. Arch Pharm (Weinheim). 2024 Mar 19:e2300628.
Molecular Weight: 430.41
Research Area: Metabolic Disease
Solubility: 10 mM in DMSO
Target: Amylases;Glucosidase