Product Description: α-Glucosidase-IN-57 (Compound 10c) is a competitive and orally active α-glucosidase inhibitor with an IC50 value of 0.180 μM and a Ki of 0.15 μM. α-Glucosidase-IN-57 can reduce fasting and overall blood glucose levels in mice, and can be used for anti-diabetes research[1].
Formula: C32H23FN4OS
References: [1]Khalili Ghomi M, et al. Evaluation of novel 2-(quinoline-2-ylthio)acetamide derivatives linked to diphenyl-imidazole as α-glucosidase inhibitors: Insights from in silico, in vitro, and in vivo studies on their anti-diabetic properties. Eur J Med Chem. 2024 Apr 5;269:116332.
Molecular Weight: 530.61
Research Area: Metabolic Disease
Solubility: 10 mM in DMSO
Target: Glucosidase