ABCG2-IN-3, CAS 1942919-63-2

Product Description: ABCG2-IN-3 (Compound 52) is a selective inhibitor for breast cancer resistance protein (ABCG2), with an IC50 of 0.238 µM. ABCG2-IN-3 reverses the ABCG2-mediated resistance toward SN-38 and inhibit the ATPase activity[1].

Formula: C25H20Cl2N2O2

References: [1]Spindler A, et al., Synthesis and Investigation of Tetrahydro-β-carboline Derivatives as Inhibitors of the Breast Cancer Resistance Protein (ABCG2). J Med Chem. 2016 Jul 14;59(13):6121-35.

CAS Number: 1942919-63-2

Molecular Weight: 451.34

Research Area: Cancer

Solubility: 10 mM in DMSO

Target: BCRP

• Artikelnummer: MEXHY-119724-0
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-119724-0
• Green Labware: Nein
• Verpackungseinheit: Get quote
• Mengeneinheit: STK