Abemaciclib (Standard), CAS 1231929-97-7

Product Description: Abemaciclib (Standard) is the analytical standard of Abemaciclib. This product is intended for research and analytical applications. Abemaciclib (LY2835219) is a selective CDK4/6 inhibitor with IC50 values of 2 nM and 10 nM for CDK4 and CDK6, respectively.

Formula: N/A

References: [1]Ku BM, et al. The CDK4/6 inhibitor LY2835219 has potent activity in combination with mTOR inhibitor in head and neck squamous cell carcinoma. Oncotarget.?2016 Mar 22;7(12):14803-13./[2]Yadav V, et al. The CDK4/6 inhibitor LY2835219 overcomes PLX4032 resistance resulting from MAPK reactivation and cyclin D1 upregulation. Mol Cancer Ther. 2014 Oct;13(10):2253-63./[3]Gelbert LM, et al. Preclinical characterization of the CDK4/6 inhibitor LY2835219: in-vivo cell cycle-dependent/independent anti-tumor activities alone/in combination with NSC 613327. Invest New Drugs. 2014 Oct;32(5):825-37.

CAS Number: 1231929-97-7

Molecular Weight: N/A

Research Area: Cancer

Target: CDK

• Artikelnummer: MEXHY-16297AR-0
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-16297AR-0
• Green Labware: Nein
• Verpackungseinheit: Get quote
• Mengeneinheit: STK