AC-186, CAS 1421854-16-1

Product Description: AC-186 is a selective non-steroidal estrogen receptor β (ERβ) agonist with EC50s of 6 nM and 5000 nM for ERβ and ERα, respectively. AC-186 shows gender selective neuroprotective effects in a male rat model of Parkinson's disease[1].

Applications: Neuroscience-Neurodegeneration

Formula: C18H17F3O

References: [1]McFarland K, et al. AC-186, a selective nonsteroidal estrogen receptor β agonist, shows gender specific neuroprotection in a Parkinson's disease rat model. ACS Chem Neurosci. 2013 Sep 18;4(9):1249-55./[2]Jian-Nong Ma, et al. Estrogen Receptor Beta Selective Agonists as Agents to Treat Chemotherapeutic-Induced Neuropathic Pain. ACS Chem Neurosci. 2016 Sep 21;7(9):1180-7.

CAS Number: 1421854-16-1

Molecular Weight: 306.32

Compound Purity: 99.61

Research Area: Neurological Disease

Solubility: DMSO : 100 mg/mL (ultrasonic)

Target: Estrogen Receptor/ERR

• Artikelnummer: MEXHY-110157-25
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-110157-25
• Green Labware: Nein
• Verpackungseinheit: 25 mg
• Mengeneinheit: STK