Product Description: ACBI1 is a potent and cooperative SMARCA2, SMARCA4 and PBRM1 degrader with DC50s of 6, 11 and 32 nM, respectively. ACBI1 is a PROTAC degrader. ACBI1 shows anti-proliferative activity. ACBI1 induces apoptosis[1].
Applications: Cancer-programmed cell death
Formula: C49H58FN9O7S
References: [1]Farnaby W, et al. BAF complex vulnerabilities in cancer demonstrated via structure-based PROTAC design. Nat Chem Biol. 2019 Jul;15(7):672-680.
CAS Number: 2375564-55-7
Molecular Weight: 936.10
Compound Purity: 98.83
Research Area: Cancer
Solubility: DMSO : ≥ 100 mg/mL
Target: Apoptosis;Epigenetic Reader Domain;PROTACs