ACBI2, CAS 2913161-19-8

Product Description: ACBI2 is a highly potent and orally active VHL PROTAC SMARCA2 degrader (EC50: 7 nM), which selectively degrades SMARCA2 with a DC50 value of 1 nM in RKO cells. ACBI2 can be used in the research of lung cancer[1].

Applications: Cancer-programmed cell death

Formula: C56H68BrFN8O5S

References: [1]Kofink C, et al. A selective and orally bioavailable VHL-recruiting PROTAC achieves SMARCA2 degradation in vivo. Nat Commun. 2022 Oct 10;13(1):5969.

CAS Number: 2913161-19-8

Molecular Weight: 1064.16

Compound Purity: 99.76

Research Area: Cancer

Solubility: DMSO : 125 mg/mL (ultrasonic)

Target: Epigenetic Reader Domain;PROTACs

• Artikelnummer: MEXHY-151623-50
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-151623-50
• Green Labware: Nein
• Verpackungseinheit: 50 mg
• Mengeneinheit: STK