Product Description: AChE/BuChE-IN-5(compound 5a) is a dual target inhibitor. AChE/BuChE-IN-5 has excellent nanomolar inhibitory activity on acetylcholinesterase (AChE)(IC50=46.9 nM) and butyryl cholinesterase (BuChE)(IC50=3.5 nM). AChE/BuChE-IN-5 can be used for Alzheimer's Disease research[1].
Formula: C19H14N4O
References: [1]Zaafar D, et al. Unleashing new MTDL AChE and BuChE inhibitors as potential anti-AD therapeutic agents: In vitro, in vivo and in silico studies[J]. International Journal of Biological Macromolecules, 2024: 131740.