AChE-IN-62

Product Description: AChE-IN-62 (Compound 1) is an effective mixed and selective acetylcholinesterase (AChE) inhibitor with an IC50 value of 0.421 μM. AChE-IN-62 exhibits excellent blood-brain barrier permeability and neuroprotective effects. Additionally, AChE-IN-62 can inhibit the aggregation of Aβ1?42 with an IC50 value of 44.64 μM. AChE-IN-62 is also an effective multi-target-directed ligand (MTDL) that can be utilized in the research of Alzheimer's disease[1].

Formula: C19H21N5O3S2

References: [1]Mishra CB, et al. Multitarget action of Benzothiazole-piperazine small hybrid molecule against Alzheimer's disease: In silico, In vitro, and In vivo investigation. Biomed Pharmacother. Published online April 1, 2024.

Molecular Weight: 431.53

Research Area: Neurological Disease

Solubility: 10 mM in DMSO

Target: Amyloid-β;Cholinesterase (ChE)

• Artikelnummer: MEXHY-161466-0
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-161466-0
• Green Labware: Nein
• Verpackungseinheit: Get quote
• Mengeneinheit: STK