Adamantanine, CAS 42381-05-5

Product Description: Adamantanine (2-Aminoadamantane-2-carboxylic acid) inhibits the transport of methionine (Ki is 0.76 mM) and leucine into Ehrlich ascites carcinoma cells. Adamantanine inhibits proliferation of P388 lymphocytic leukemia cells with an IC50 of >1 mM. Adamantanine inhibits the leucine aminopeptidase with an I/S0.5 of 10.5[1].

Applications: Cancer-programmed cell death

Formula: C11H17NO2

References: [1]Nagasawa HT, et al., Potential latentiation forms of biologically active compounds based on action of leucine aminopeptidase. Dipeptide derivatives of the tricycloaliphatic alpha-amino acid, adamantanine. J Med Chem. 1975 Aug;18(8):826-30./[2]Nagaswa HT, et al., 2-Aminoadamantane-2-carboxylic acid, a rigid, achiral, tricyclic alpha-amino acid with transport inhibitory properties. J Med Chem. 1973 Jul;16(7):823-6.

CAS Number: 42381-05-5

Molecular Weight: 195.26

Compound Purity: 95.0

Research Area: Cancer

Solubility: 10 mM in DMSO

Target: Aminopeptidase

• Artikelnummer: MEXHY-121123-0
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-121123-0
• Green Labware: Nein
• Verpackungseinheit: Get quote
• Mengeneinheit: STK