ADAMTS-5-IN-2, CAS 294648-66-1

Product Description: ADAMTS-5-IN-2 (compound 25) is a potent ADAMTS-5 inhibitor with an IC50 value of 0.71 µM. ADAMTS-5-IN-2 has the potential for the research of modifying osteoarthritis[1][2].

Applications: COVID-19-immunoregulation

Formula: C17H15N3OS

References: [1]Bompiani KM, et al. High-Throughput Screening Uncovers Novel Botulinum Neurotoxin Inhibitor Chemotypes. ACS Comb Sci. 2016 Aug 8;18(8):461-74./[2]Matthew G. Bursavich; et al. 5′-Phenyl-3′H-spiro[indoline-3,2′-[1,3,4]thiadiazol]-2-one inhibitors of ADAMTS-5 (Aggrecanase-2). Bioorganic & Medicinal Chemistry Letters. 2007, 17(20), 5630-5633.

CAS Number: 294648-66-1

Molecular Weight: 309.39

Compound Purity: 98.73

Research Area: Inflammation/Immunology

Solubility: DMSO : 100 mg/mL (ultrasonic)

Target: ADAMTS

• Artikelnummer: MEXHY-135710-10.1
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-135710-10.1
• Green Labware: Nein
• Verpackungseinheit: 10mM/1mL
• Mengeneinheit: STK