Adavosertib (Standard), CAS 955365-80-7

Product Description: Adavosertib (Standard) is the analytical standard of Adavosertib. This product is intended for research and analytical applications. Adavosertib (AZD-1775; MK-1775) is a potent Wee1 inhibitor with an IC50 of 5.2 nM.

Formula: N/A

References: [1]Hirai H, et al. MK-1775, a small molecule Wee1 inhibitor, enhances anti-tumor efficacy of various DNA-damaging agents, including 5-FU. Cancer Biol Ther. 2010 Apr;9(7):514-22./[2]Bridges KA, et al. MK-1775, a novel Wee1 kinase inhibitor, radiosensitizes p53-defective human tumor cells. Clin Cancer Res. 2011 Sep 1;17(17):5638-48. Epub 2011 Jul 28./[3]Rajeshkumar NV, et al. MK-1775, a potent Wee1 inhibitor, synergizes with NSC 613327 to achieve tumor regressions, selectively in p53-deficient pancreatic cancer xenografts.Clin Cancer Res. 2011 May 1;17(9):2799-806. Epub 2011 Mar 9.

CAS Number: 955365-80-7

Molecular Weight: N/A

Research Area: Cancer

Target: Wee1

• Artikelnummer: MEXHY-10993R-0
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-10993R-0
• Green Labware: Nein
• Verpackungseinheit: Get quote
• Mengeneinheit: STK