Alkyne-phenol, CAS 1694495-59-4

Product Description: Alkyne-phenol (Alk-Ph) is a clickable ascorbate peroxidase 2 (APEX2) probe. Alkyne-phenol substantially improves APEX-labeling efficiency in intact yeast cells, as it is more cell wall-permeant than APEX2 substrate biotin-phenol (BP). Alkyne-phenol also facilitates the identification of APEX-labeling sites, allowing the unambiguous assignment of membrane topology of mitochondrial proteins[1]. Alkyne-phenol is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

Formula: C13H15NO2

References: [1]Li Y, et al. A Clickable APEX Probe for Proximity-Dependent Proteomic Profiling in Yeast. Cell Chem Biol. 2020;27(7):858-865.e8.

CAS Number: 1694495-59-4

Molecular Weight: 217.26

Compound Purity: 99.45

Research Area: Others

Solubility: DMSO : 50 mg/mL (ultrasonic)

Target: Others

• Artikelnummer: MEXHY-131442-5
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-131442-5
• Green Labware: Nein
• Verpackungseinheit: 5 mg
• Mengeneinheit: STK