Product Description: Aloisine B (compound 9) is a cyclin-dependent kinase (CDK) inhibitor. Aloisine B inhibits cell proliferation by arresting cells in both G1 and G2 via competing with ATP-binding pocket[1].
Applications: Cancer-Kinase/protease
Formula: C15H14ClN3
References: [1]Yvette Mettey, et al. Aloisines, a new family of CDK/GSK-3 inhibitors. SAR study, crystal structure in complex with CDK2, enzyme selectivity, and cellular effects. J Med Chem. 2003, 46, 2.
CAS Number: 496864-14-3
Molecular Weight: 271.74
Research Area: Others
Solubility: 10 mM in DMSO
Target: CDK