Amiloride hydrochloride dihydrate (Standard), CAS 17440-83-4

Product Description: Amiloride hydrochloride dihydrate (Standard) is the analytical standard of Amiloride hydrochloride dihydrate. This product is intended for research and analytical applications. Amiloride hydrochloride dihydrate (MK-870 hydrochloride dihydrate) is an inhibitor of both epithelial sodium channel (ENaC[1]) and urokinase-type plasminogen activator receptor (uTPA[2]). Amiloride hydrochloride dihydrate is a blocker of polycystin-2 (PC2; TRPP2[3]) channel.

Formula: N/A

References: [1]Miller RL, et al. Blockade of ENaCs by amiloride induces c-Fos activation of the area postrema. Brain Res. 2015 Mar 19;1601:40-51./[2]Xu LB, et al. Amiloride, a urokinase-type plasminogen activator receptor (uTPA) inhibitor, reduces proteinurea in podocytes. Genet Mol Res. 2015 Aug 14;14(3):9518-29./[3]Giamarchi A, et al. A polycystin-2 (TRPP2) dimerization domain essential for the function of heteromeric polycystin complexes. EMBO J. 2010 Apr 7;29(7):1176-91.

CAS Number: 17440-83-4

Molecular Weight: N/A

Research Area: Metabolic Disease; Cardiovascular Disease

Target: Apoptosis;Sodium Channel;TRP Channel

• Artikelnummer: MEXHY-B0285BR-0
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-B0285BR-0
• Green Labware: Nein
• Verpackungseinheit: Get quote
• Mengeneinheit: STK