Antibacterial agent 206

Product Description: Antibacterial agent 206 (Compound 10e) is a indolylacryloyl-derived oxacins, which exhibits broad antibacterial spectrum with MIC of 0.25-1 μg/mL. Antibacterial agent 206 reduces the exopolysaccharide, eliminates the biofilm, and thus attenuates the drug resistance. Antibacterial agent 206 exhibits antibacterial activity through destory of membrane integrity, accumulation of reactive oxygen species ROS, and inhibition of DNA replication[1].

Applications: COVID-19-immunoregulation

Formula: C30H28FN5O5

References: [1]Hu YG, et al., Discovery of indolylacryloyl-derived oxacins as novel potential broad-spectrum antibacterial candidates. Eur J Med Chem. 2024 Apr 15;270:116392.

Molecular Weight: 557.57

Research Area: Infection

Solubility: 10 mM in DMSO

Target: Bacterial

• Artikelnummer: MEXHY-162430-0
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-162430-0
• Green Labware: Nein
• Verpackungseinheit: Get quote
• Mengeneinheit: STK