Anticancer agent 199, CAS 2422001-24-7

Product Description: Anticancer agent 199 (Compound G-4) induces apoptosis in triple negative breast cancer (TNBC) cells via the mitochondrial pathway through inhibiting EGFR, AKT and MAPK pathways. Anticancer agent 199 also induces Ferroptosis by down-regulating LCN2. Anticancer agent 199 inhibits TNBC cell viability and migration, and induces S phase cell cycle arrest. Anticancer agent 199 is a derivate of cyclin-dependent kinase inhibitor Rocovitine[1].

Formula: C29H39ClFN7O

References: [1]Sun G, et al. G-4 inhibits triple negative breast cancer by inducing cell apoptosis and promoting LCN2-dependent ferroptosis. Bioc

CAS Number: 2422001-24-7

Molecular Weight: 556.12

Research Area: Cancer

Solubility: 10 mM in DMSO

Target: Apoptosis;Ferroptosis

• Artikelnummer: MEXHY-158049-0
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-158049-0
• Green Labware: Nein
• Verpackungseinheit: Get quote
• Mengeneinheit: STK