Antimalarial agent 38, CAS 123580-46-1

Product Description: Antimalarial agent 38 (Compound 1) exhibits activity against antiplasmodial, which inhibits Plasmodium falciparum D6 strain, chloroquine-sensitive Thai strain and chloroquine-resistant FcB1 strain and K1 strain, with IC50s of 0.5, 13, 1 and 13 μM, respectively. Antimalarial agent 38 is non-cytotoxic for mammalian cells MCR58 (IC50 >140 μM). Antimalarial agent 38 improves the survival rate of Plasmodium yoelii nigeriensis infected mouse model[1].

Formula: C36H40N2O12

References: [1]Auffret G, et al., Synthesis and antimalarial evaluation of a series of piperazinyl flavones. Bioorg Med Chem Lett. 2007 Feb 15;17(4):959-63.

CAS Number: 123580-46-1

Molecular Weight: 692.71

Compound Purity: 99.55

Research Area: Infection

Target: Parasite

• Artikelnummer: MEXHY-157892-1
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-157892-1
• Green Labware: Nein
• Verpackungseinheit: 1 mg
• Mengeneinheit: STK