Antitumor agent-156

Product Description: Antitumor agent-156 (Compound 20) causes DNA damage and mitochondrial dysfunction, promotes reactive oxygen speciesgeneration, activates endoplasmic reticulum stress, and induce apoptosis, autophagy and ferroptosis. Antitumor agent-156 shows superior antitumor activity against cancer cells including Cisplatin (HY-17394) resistance cells. Antitumor agent-156 displayS good liver-targeting ability[1].

Formula: C48H78Cl3N5O12Pt

References: [1]Huang X, et al. Glycyrrhetinic Acid as a Hepatocyte Targeting Ligand-Functionalized Platinum(IV) Complexes for Hepatocellular Carcinoma Therapy and Overcoming Multidrug Resistance. J Med Chem. 2024 May 23;67(10):8020-8042.

Molecular Weight: 1218.60

Research Area: Cancer

Target: Apoptosis;Autophagy;Ferroptosis;Reactive Oxygen Species

• Artikelnummer: MEXHY-161647-0
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-161647-0
• Green Labware: Nein
• Verpackungseinheit: Get quote
• Mengeneinheit: STK