Product Description: Apoptosis inducer 19 (Compound 7g) is an Apoptosis inducer. Apoptosis inducer 19 elevates expression of pro-apoptotic proteins (Bax and caspase-3) and downregulates anti-apoptotic protein (Bcl-2). Apoptosis inducer 19 upregulates cellular reactive oxygen species (ROS) levels and disrupts mitochondrial membrane potential (MMP). Apoptosis inducer 19 can be used for triple-negative breast cancer (TNBC) research[1].
Formula: C22H23NO4
References: [1]Kumar P, et al. Design, synthesis, and biological evaluation of chalcone acetamide derivatives against triple negative breast cancer. Bioorg Med Chem Lett. 2024 Jul 15;107:129795.
Molecular Weight: 365.42
Research Area: Cancer
Target: Apoptosis;Bcl-2 Family;Caspase;Reactive Oxygen Species