Apremilast (Standard), CAS 608141-41-9

Product Description: Apremilast (Standard) is the analytical standard of Apremilast. This product is intended for research and analytical applications. Apremilast (CC-10004) is an orally available inhibitor of type-4 cyclic nucleotide phosphodiesterase (PDE-4) with an IC50 of 74 nM. Apremilast inhibits TNF-α release by lipopolysaccharide (LPS) with an IC50 of 104 nM[1].

Formula: N/A

References: [1]Perez-Aso M, et al. Apremilast, a novel phosphodiesterase 4 (PDE4) inhibitor, regulates inflammation through multiple cAMP downstream effectors. Arthritis Res Ther. 2015 Sep 15;17:249./[2]Chen LG, et al. Determination of Apremilast in Rat Plasma by UPLC-MS-MS and Its Application to a Pharmacokinetic Study. J Chromatogr Sci. 2016 Sep;54(8):1336-40.

CAS Number: 608141-41-9

Molecular Weight: N/A

Research Area: Inflammation/Immunology

Target: Apoptosis;Phosphodiesterase (PDE);TNF Receptor

• Artikelnummer: MEXHY-12085R-0
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-12085R-0
• Green Labware: Nein
• Verpackungseinheit: Get quote
• Mengeneinheit: STK