Articaine (hydrochloride), CAS 23964-57-0

Product Description: Articaine hydrochloride (Hoe-045) is an amide anaesthetic containing an ester group, reversibly binding to the α-subunit of the voltage-gated sodium channels within the inner cavity of the nerve, can provide effective pain relief. Articaine hydrochloride ameliorates LPS-induced acute kidney injury via inhibition of NF-ĸB activation and the NLRP3 inflammasome pathway[1][2][3].

Applications: Neuroscience-Neuromodulation

Formula: C13H21ClN2O3S

References: [1]Yapp KE, et al. Articaine: a review of the literature. Br Dent J. 2011 Apr 9;210(7):323-9./[2]Zhao G, et al. Local anesthetic articaine ameliorates LPS-induced acute kidney injury via inhibition of NF-ĸB activation and the NLRP3 inflammasome pathway. J Biochem Mol Toxicol. 2020 Oct;34(10):e22554./[3]Snoeck M. Articaine: a review of its use for local and regional anesthesia. Local Reg Anesth. 2012;5:23-33.

CAS Number: 23964-57-0

Molecular Weight: 320.84

Compound Purity: 98.46

Research Area: Neurological Disease

Solubility: DMSO : 100 mg/mL (ultrasonic)/H2O : 100 mg/mL (ultrasonic)

Target: NF-κB;NOD-like Receptor (NLR);Sodium Channel

• Artikelnummer: MEXHY-B0516-25
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-B0516-25
• Green Labware: Nein
• Verpackungseinheit: 25 mg
• Mengeneinheit: STK