Atazanavir (Standard), CAS 198904-31-3

Product Description: Atazanavir (Standard) is the analytical standard of Atazanavir. This product is intended for research and analytical applications. Atazanavir (BMS-232632), a highly selective HIV-1 protease inhibitor, is the first protease inhibitor approved for once-daily administration[1]. Atazanavir (BMS-232632) is a substrate and inhibitor of CYP3A4, and an inhibitor and inducer of P-glycoprotein (P-gp)[2]. Atazanavir is also a SARS-CoV 3CLpro inhibitor with an IC50 of 3.49 μM[3].

Formula: N/A

References: [1]Havlir DV, et al. Atazanavir: new option for treatment of HIV infection. Clin Infect Dis. 2004 Jun 1;38(11):1599-604./[2]Wood R. Atazanavir: its role in HIV treatment. Expert Rev Anti Infect Ther. 2008 Dec;6(6):785-96./[3]Qi Sun, et al. Bardoxolone and bardoxolone methyl, two Nrf2 activators in clinical trials, inhibit SARS-CoV-2 replication and its 3C-like protease. Signal Transduct Target Ther. 2021 May 29;6(1):212.

CAS Number: 198904-31-3

Molecular Weight: N/A

Research Area: Infection; Cancer

Target: Cytochrome P450;Endogenous Metabolite;HIV;HIV Protease;P-glycoprotein;SARS-CoV

• Artikelnummer: MEXHY-17367R-0
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-17367R-0
• Green Labware: Nein
• Verpackungseinheit: Get quote
• Mengeneinheit: STK